Leonardo Lupori

Ph.D. Student in Neuroscience

Scuola Normale Superiore

Biography

I’m a Ph.D. student in Neuroscience at Scuola Normale Superiore. I love to apply a quantitative approach to neurophysiology and behavior in mice to study how the cerebral cortex functions.

Interests

Neuroscience
Imaging
Behavior

Education

MSc in Cellular and Molecular Biology, 2015
University of Pisa
BSc in Biological Sciences, 2013
University of Pisa

Skills

Code & Electronics

MATLAB
Python
C++ (Arduino)
3D-Printing

Imaging

Two-Photon Ca²⁺ imaging
Intrinsic Signal
Widefield Ca²⁺ imaging

Wet Lab

Mice handling
PCR
IHC

Experience

Ph.D Student

Scuola Normale Superiore - Pizzorusso Lab

Sep 2015 – Present Pisa

Neurophysiology and plasticity of the visual cortex

Effects of the Gut Microbiome on visual cortical plasticity
Perineuronal Nets (PNNs) and plasticity
The visual system as a biomarker in CDKL5 deficiency disorder

Summer Internship

Harvard Medical School - Chinfei Chen Lab

Jun 2014 – Sep 2014 Boston

Two-photon Ca²⁺ imaging of retino-geniculate axonal boutons in slices
Winner of the Armenise-Harvard Summer Fellowship

Master’s Thesis

University of Pisa - Pizzorusso Lab

Jan 2014 – Dec 2015 Pisa

Visual cortical Plasticity

Development of a custom Intrinsic Signal Imaging setup
Perineuronal Nets

Bachelor’s Thesis

University of Pisa - Pizzorusso Lab

Sep 2012 – Sep 2013 Pisa

In-Vivo Two-photon imaging of dendritic spines.

Awards

Winner of the Summer Fellowship

Giovanni Armenise Foundation Jun 2014

Highly competitive fellowship for Master’s students to do research in one of the Harvard Medical School Labs in the summer

Projects

Featured Publications

3D Printable Device for Automated Operant Conditioning in the Mouse

Operant conditioning (OC) is a classical paradigm and a standard technique used in experimental psychology in which animals learn to …

Raffaele Mazziotti, Giulia Sagona, Leonardo Lupori, Virginia Martini and Tommaso Pizzorusso

PDF DOI

3D Printable Device for Automated Operant Conditioning in the Mouse

Site-specific abnormalities in the visual system of a mouse model of CDKL5 deficiency disorder

CDKL5 deficiency disorder (CDD) is a neurodevelopmental disorder characterized by a severe global developmental delay and early-onset …

Leonardo Lupori, Giulia Sagona, Claudia Fuchs, Raffaele Mazziotti, Antonia Stefanov, Elena Putignano, Debora Napoli, Enrica Strettoi, Elisabetta Ciani, Tommaso Pizzorusso

PDF DOI